Alcohol is the most common "date rape drug". Use of alcohol is never an excuse for rape. Alcohol does not cause someone to rape, it's just an excuse.

Rohypnol generally appears in tablet form. Once dissolved in a drink it is odorless. It may cause a drink to appear cloudy or release small floating bits. These are steps the manufacturer has taken to make the drug more noticeable in a drink. However, you may not notice this in a dark drink or bottle. Rohypnol is known on the street as Roofies, Roche, R-Z, Rope, Stupify, Shays, and R-2.

GHB is a clear liquid, slightly thicker than water. It generally has a mild, indistinct odor and a slightly salty taste. It also appears in powder or capsule form. GHB is known as Grievous Bodily Harm, Liquid Ecstasy, Liquid E, Liquid X, Easy Lay, Scoop, and Great Hormones at Bedtime.

Ketamine is a veterinary medicine produced in liquid and powder form. It is known on the street as Special K.